I was a long time Throwing Muses fan (still am) but I still love Kristin Hersh's solo work, which tends more to the acoustic side of things. It's hard to pick just one song as a favorite. But this one - a song that really is, in my view, two songs - floats to the top.
The first half of the song is an angry, string-filled piece that seems to be a tribute to Kristin's bipolar disorder. The second half, when the video switches to color, seems to be more reflective on the same subject matter. At any rate, it is a masterfully crafted song. Check it out!